SubtiBank SubtiBank
sdpA [2019-02-04 15:51:59]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

sdpA [2019-02-04 15:51:59]

required for SdpC toxin maturation
locus
BSU33750
pI
9.77
mw
18.51 kDa
protein length
158 aa Sequence Blast
gene length
477 bp Sequence Blast
function
maturation of the SdpC toxin
product
unknown
essential
no
synonyms
yvaW
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins]

    • Gene

    Coordinates
    3,464,289 3,464,765

    The protein

    [SW|Localization]

  • cytoplasm [Pubmed|23687264]

    • Expression and Regulation

    Operons

    genes
    [gene|219092C574A13B81CD312AEB55BAE48A3C541FB7|sdpA]-[gene|073D63E17C8248BE39F331FDE9902E21A34056D5|sdpB]-[gene|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC]
    description
    [Pubmed|12817086]

    regulatory mechanism

  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: activation, [PubMed|14651647,15687200], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon]
  • [protein|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|Rok]: repression, [Pubmed|15743949], in [regulon|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|Rok regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [PubMed|15687200,17720793], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647,15687200 PubMed]

    • additional information

  • the amount of the mRNA is substantially decreased upon depletion of [gene|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [PubMed|21815947]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-A453 (yvaW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/453 NBRP B. subtilis, Japan]
  • BKE33750 ([gene|219092C574A13B81CD312AEB55BAE48A3C541FB7|sdpA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33750 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTACAGTAATAATTCCCT, downstream forward: _UP4_GTATGAAGATATTAAATAGT
  • BKK33750 ([gene|219092C574A13B81CD312AEB55BAE48A3C541FB7|sdpA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33750 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTACAGTAATAATTCCCT, downstream forward: _UP4_GTATGAAGATATTAAATAGT

    • References

    Reviews

  • 20955377

    • Original Publications

  • 12817086,14651647,15687200,15743949,15687200,17720793,12850135,23687264,21815947